I think the big companies will be okay, but the smaller companies will struggle. Sure, there will be some small cap outliers, but the large caps have been positioning themselves since before COVID. For example, WMT is gaining market share in groceries and that's a trend that will only increase. Even without a pandemic, it's much more convenient to have someone else do the shopping for you. MSFT will be used pandemic or not, especially the collaboration tools.
Drug companies are very hit or miss and the ones that don't pay a dividend are mostly nothing but a speculation. It's ironic how long term share holders of PFE are singing in the rain right now. MRNA has a PE of 50 today and that's because it is pricing in a booster for many years ahead.
Now is the time to get in on those re-opening stocks if you're into individual stock picking. Think travel, leisure, cruises here. By time the numbers start looking better, it will be too late. TSP wise, S fund already had it's time in the sun last year. C fund should be the equity fund to overweight going forward.
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